- Consultant-led Gynaecology care
- Follow-up call with Lead Consultant
- Non-invasive Saliva Test
- From £1,175
What is the Ziwig Endotest® for endometriosis?
The Ziwig Endotest® is a non-invasive saliva test used to help identify endometriosis, a debilitating gynaecological condition.
If you’re experiencing symptoms such as bleeding after sex or severe menstrual pain, a private endometriosis test like the Ziwig Endotest® can help you take the next step towards treatment and relief.
At Pall Mall Medical, you don’t have to wait. You can choose to take the test without a consultation or you can choose to book a consultation with our gynaecology specialist before the test to discuss endometriosis diagnosis options. You’re not alone.
Endometriosis tests: How is endometriosis diagnosed in the UK?
In the UK, endometriosis tests are usually done by the NHS and in private clinics. It’s worth noting that the NHS has lengthy wait times, and currently three-quarters of a million of UK women are waiting to see a gynaecologist.
We know how frustrating this can be, especially because there is a chance that your endometriosis will get worse while you wait. This is why many women choose to have an endometriosis test in a private clinic.
At Pall Mall Medical, we help to diagnose endometriosis via a quick and easy saliva test - the Ziwig Endotest. Instead of surgery or internal examinations, the Ziwig Endotest uses your saliva sample to detect specific biomarkers associated with endometriosis. Where endometriosis usually takes years to diagnose, the Ziwig Endotest provides answers within a matter of days.
Endometriosis test FAQs
What is an endometriosis test and how does it work?
An endometriosis test exists to detect early endometriosis. At Pall Mall Medical, we use a test called the Ziwig Endotest. The test helps to identify bio-markers associated with endometriosis. It is quick and pain-free.
Is there a non-invasive test for endometriosis in the UK?
Yes - there is a non-invasive endometriosis test in the UK - and it is called the Ziwig Endotest. This test uses a saliva sample as a way of early detection. It’s important to note that a laparoscopy (surgery) may be needed to confirm an endometriosis diagnosis.
How accurate is an endometriosis test?
According to a 2025 study, the Ziwig Endotest is 96.6% accurate. Furthermore, 9 out of 10 women who tested during the study were given an accurate test result. To learn more about the clinical studies of Ziwig Endotest, please get in touch with our expert gynae team.
What are the benefits of having the Ziwig Endotest?
There are many benefits to having the Ziwig Endotest over traditional blood tests and endometriosis surgery, such as:
- It’s non-invasive and only requires saliva, no needles!
- It’s 96.6% accurate
- It will get to the bottom of your symptoms early on
- It supports quicker access to treatment
Who should consider having an endometriosis test?
If you are experiencing endometriosis symptoms and have not yet been diagnosed with endometriosis, then an endometriosis test such as the Ziwig Endotest could be for you. The symptoms of endometriosis includes pain after sex and heavy periods.
Can the Ziwig Endotest replace laparoscopy?
No, the Ziwig Endotest does not replace laparoscopy. Usually, the Ziwig Endotest is used to detect endometriosis, whereas laparoscopy confirms the diagnosis and allows your surgeon to remove the tissue-like legions.
Why does early endometriosis testing matter?
If left untreated, endometriosis can spread to other parts of your body, and potentially worsen. Stage 4 endometriosis is a very serious condition which can lead to infertility and damage to the surrounding organs.
What is endometriosis?
Endometriosis is an extremely painful condition where cells (similar to the tissue-like lining of the womb) grow in different parts of the female organ - including on the ovaries and fallopian tubes. The condition comes with lots of hard-to-manage symptoms, and women often describe the pain as far worse than that of a period. It’s important to know that endometriosis has no cure, but if you are diagnosed early enough, you can stop it spreading and causing serious problems.
What are the signs and symptoms of endometriosis?
Endometriosis sounds like a simple condition, but in reality, it is one of the toughest conditions for a woman to live with. If you have endometriosis or signs of endometriosis, you may be experiencing the following:
Pelvic Pain That Feels Constant: Ongoing or recurring pain in the pelvis, lower abdomen, or back, not limited to periods.
Heavy or Irregular Bleeding: Missing periods or spotting between cycles and experiencing very heavy periods when you do get a period., & large clots
Vomiting or Migraines During Your Period: Nausea, vomiting, or severe headaches that occur on or around your period that can disrupt daily life.
Severe Ovulation or Period Pain: Intense, often debilitating cramps that disrupt your daily life.
Pain During or After Sex: Deep, persistent or even excruciating pain linked to sexual intercourse is a very common symptom.
Problems Conceiving: Endometriosis can make it harder to conceive. This can be due to inflammation, scar tissue blocking fallopian tubes, or affecting the ovaries.
Endometriosis doesn’t look the same for everybody; but it’s important to detect the condition before it spreads and manifests. It’s particularly important to catch stage 4 endometriosis because it can cause infertility and if left untreated, can cause damage to your surrounding organs.
If you have symptoms of endometriosis, then we feel for you. It’s not an easy condition to live with. Remember that if you’re experiencing endometriosis symptoms, you can book an in-depth consultation with our gynae experts today. They can offer you 24/7 support and you won’t have to continue to wait in the NHS queue. Once your endometriosis has been diagnosed, you’ll be able to go ahead and get treatment for it.
Who is the Ziwig Endotest suitable for?
The Ziwig Endotest is suitable for any woman between the ages of 18 and 43 whose:
- symptoms have not been investigated yet
- symptoms have been dismissed
- symptoms have been left to develop because of long NHS waiting times
If you would like further information about your suitability for the Ziwig Endotest, please get in touch with our expert gynae team today. You’ve got this - we’re right here with you!
What to expect from your appointment
When you book your Ziwig Endotest, you can skip the pre-consultation process altogether. This means that you attend either our clinics in Manchester or Newton-le-Willows, give your saliva sample, then you’ll go straight home to wait for our clinician to call you with the results. You can go about your day as normal while your sample makes its way to the lab. It’s a quick and easy process. If you have any questions beforehand, you can call our expert gynae team.
Your Ziwig Endotest results: What do they mean?
Once your results come back from the lab, your clinician will call you with the results. There are 3 types of results: positive, negative and inconclusive.
Here is what the results mean:
A positive result means that it’s highly likely you have endometriosis and that there is a presence of it in your body. Further investigations like laparoscopy may be needed. Some women choose to opt for medical management instead.
A negative result means it’s unlikely that endometriosis is present, but you should not completely rule it out.
An inconclusion result means that you may have to repeat testing
Booking your test is the first big step, and you can overcome that today. Once you’ve had your test, our gynae team will help you with next steps, including medications referrals, and ways to look after yourself at home.
The benefits of Ziwig Endotest: A Non-Invasive Endometriosis Test
There are many benefits of having the Ziwig Endotest before a laparoscopy or surgical diagnostic test.
✔ Helps to identify endometriosis early on
✔ Non-invasive and pain-free
✔ No surgery or needles
✔ No recovery time needed
✔ Avoids unnecessary surgery - such as a laparoscopy - in some patients
✔ Strengthens referrals to gynaecology specialists
✔ Mitigates the need for having a laparoscopy or surgical biopsy and it being 'all for nothing' if your results are negative
Please remember that you might need a laparoscopy further down the line. The Ziwig Endotest helps with early detection and minimises the need for a laparoscopy.
Why should I trust the Ziwig Endotest?
According to a 2025 clinical study, the Ziwig Endotest is 96.6% accurate. The study enrolled 971 symptomatic women aged 18 to 43 years, and 9 out of 10 reported an accurate result.
The Ziwig Endotest has been shown to perform consistently across all patient groups — whether you’re on hormonal treatment, using pain relief, or being tested at different clinics. This means you can trust the test to be reliable and consistent regardless of your situation. To learn more about the Ziwig Endotest and its clinical excellence, get in touch with our expert gynae team here.
Ziwig Endotest vs laparoscopy for endometriosis diagnosis
When diagnosing endometriosis, the Ziwig Endotest cannot replace a laparoscopy. In fact, both tests work together to create a clearer diagnosis.
Your first step is often the Ziwig Endotest — a pain-free, non-invasive saliva test that can help detect endometriosis at an earlier stage.
If needed, you will then have a laparoscopy (surgical biopsy) to confirm your endometriosis diagnosis. Your gynae specialist can also remove the tissue-like legions at the same time as taking the biopsy. Try not to worry - you’ll be under full anaesthetic and you won’t feel a thing.
How much does the Ziwig Endotest cost in the UK?
The cost of the Ziwig Endotest depends on the location of the procedure, the provider, and the clinician doing the procedure. At Pall Mall Medical, our Ziwig Endotests cost just £1,175.
If you would like to discuss our flexible finance options like Klarna and Clearpay, please get in touch with our friendly team today. They can also advise on the cost of a laparoscopy and other, similar procedures.
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