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Ovarian Cancer Screening

Private Ovarian Cancer Screening

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Ovarian cancer is the fifth most common cause of cancer-related death among UK women and causes 5% of all cancer deaths in women worldwide. 

Ovarian cancer can be difficult to diagnose as the symptoms are often similar to other health conditions and include a loss of appetite, frequent urination and bloating, amongst other symptoms. This is one reason why ovarian cancer is often diagnosed at an advanced stage, meaning that a poor survival rate is likely. However, by detecting suspected ovarian cancer early, women are far more likely to survive the illness.

Pall Mall Medical offer two different types of blood tests to help diagnose ovarian cancer:


CA 125 Blood Test

  • Detection of the CA 125 protein in your blood may indicate the presence of ovarian cancer
  • Early detection can increase the rates of survival as only a third of the 6,800 women diagnosed survive for five years. Early detection can increase the survival rate to 90% of women
  • While symptoms don't automatically mean you have ovarian cancer, it is advisable to be aware of them and be tested if they don't seem to subside.


HE4 (HE4 and ROMA)

  • HE4 is a new marker which is over-expressed in patients with ovarian cancer. (This test is not currently available on the NHS)
  • ROMA – a Risk of Ovarian Malignancy Algorithm classifies patients as being at high or low risk for malignant disease using both the CA 125 and HE4 results. It estimates the risk of finding ovarian cancer during surgery
  • When combined with CA 125, this significantly raises the level of sensitivity for the detection.


Which Test is Most Suitable for You?

Recent studies have shown that, for pre-menopausal women, the combined CA125 & HE4 blood test is more accurate than the single CA125 test for detecting ovarian cancer. The research (summarised at the bottom of page) is supported be many Consultant Gynaecologists across the world.
The CA125 test is also included within our popular Well Woman Over 45 Health Screen, with the HE4 combination test a popular add-on.

Private ovarian cancer screening prices



CA125 Blood Test

(excludes appointment, from £25)


HE4 Blood Test

(excludes appointment, from £25)


Combined CA125 & HE4 Blood Test

(excludes appointment, from £25)


Ovarian Cancer Health Screen

(includes Gynaecology Consultation, combined CA125 & HE4 Blood test, Ovarian Ultrasound Scan



Book with Confidence

For more information or to book your Ovarian Cancer Test, please feel welcome to call us on 03300 58 44 55 or email Alternatively you can complete our online enquiry form at the top of the page and our team will contact you back.


More About Ovarian Cancer Screening:

Paper Summary:
From the Departments of Obstetrics and Gynecology, and Radioisotope Laboratory at Xuzhou Central Hospital

To assess the ability of human epididymis protein 4 (HE4) and CA-125 to distinguish among benign, borderline, and malignant pelvic masses in premenopausal women.
Of 229 premenopausal patients, 195 (85%) had benign masses, 18 (8%) had EOC, and 16 (7%) had borderline ovarian tumor. The sensitivity of CA-125 and HE4 for EOC detection was 83.3% and 88.9%, respectively. The specificity of CA-125 and HE4 was 59.5% and 91.8%, respectively. A normal HE4 level ruled out invasive cancer in 98% of women with an elevated CA-125.
HE4 offers superior specificity compared to CA-125 for the differentiation of benign and malignant adnexal masses in premenopausal women.